abstract：BACKGROUND:Generalized anxiety disorder (GAD) is highly co-morbid with depression. Depression is associated with elevated levels of the inflammation marker C-reactive protein (CRP), cross-sectionally and over time. To date, no studies have looked at the association between CRP and GAD. METHOD:A total of nine waves of ...

journal_title：Psychological medicine

authors： Copeland WE,Shanahan L,Worthman C,Angold A,Costello EJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Retrospective studies have consistently indicated an association between maladaptive parenting and borderline personality disorder (BPD). This requires corroboration with prospective, longitudinal designs. We investigated the association between suboptimal parenting and parent conflict in childhood and BPD s...

journal_title：Psychological medicine

authors： Winsper C,Zanarini M,Wolke D

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The base rate of transition from subthreshold psychotic experiences (the exposure) to clinical psychotic disorder (the outcome) in unselected, representative and non-help-seeking population-based samples is unknown. METHOD:A systematic review and meta-analysis was conducted of representative, longitudinal p...

journal_title：Psychological medicine

authors： Kaymaz N,Drukker M,Lieb R,Wittchen HU,Werbeloff N,Weiser M,Lataster T,van Os J

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Belief inflexibility is a thinking style observed in patients with schizophrenia, in which patients tend to refute evidence that runs counter to their prior beliefs. This bias has been related to a dominance of prior expectations (prior beliefs) over incoming sensory evidence. In this study we investigated t...

journal_title：Psychological medicine

authors： Barbalat G,Rouault M,Bazargani N,Shergill S,Blakemore SJ

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Cognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study ...

journal_title：Psychological medicine

authors： Andersson E,Enander J,Andrén P,Hedman E,Ljótsson B,Hursti T,Bergström J,Kaldo V,Lindefors N,Andersson G,Rück C

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Older adults have the lowest prevalence and incidence of major depressive disorder, although it has been hypothesized that this finding is due in part to differences in expression of psychopathology in later life. The aim of this study was to examine variation in depressive symptomatology in the general popu...

journal_title：Psychological medicine

authors： Mezuk B,Kendler KS

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The National Psychiatric Morbidity Survey (NPMS) programme was partly designed to monitor trends in mental disorders, including depression, with comparable data spanning 1993 to 2007. Findings already published from this programme suggest that concerns about increasing prevalence of common mental disorders (...

journal_title：Psychological medicine

authors： Spiers N,Brugha TS,Bebbington P,McManus S,Jenkins R,Meltzer H

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Research on the structure of co-morbidity among common mental disorders has largely focused on current prevalence rather than on the development of co-morbidity. This report presents preliminary results of the latter type of analysis based on the US National Comorbidity Survey Replication Adolescent Suppleme...

journal_title：Psychological medicine

authors： Kessler RC,Avenevoli S,McLaughlin KA,Green JG,Lakoma MD,Petukhova M,Pine DS,Sampson NA,Zaslavsky AM,Merikangas KR

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Cannabis use is associated with an earlier age at onset of psychotic illness. The aim of the present study was to examine whether this association is confounded by gender or other substance use in a large cohort of patients with a non-affective psychotic disorder. METHOD:In 785 patients with a non-affective...

journal_title：Psychological medicine

authors： Dekker N,Meijer J,Koeter M,van den Brink W,van Beveren N,Kahn RS,Linszen DH,van Os J,Wiersma D,Bruggeman R,Cahn W,de Haan L,Krabbendam L,Myin-Germeys I,GROUP Investigators.

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Psychotic symptoms occur more frequently in the general population than psychotic disorder and index risk for psychopathology. Multiple studies have reported on the prevalence of these symptoms using self-report questionnaires or clinical interviews but there is a lack of consensus about the prevalence of ps...

journal_title：Psychological medicine

authors： Kelleher I,Connor D,Clarke MC,Devlin N,Harley M,Cannon M

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Improving the quality of mental health care requires integrating successful research interventions into 'real-world' practice settings. Coordinated Anxiety Learning and Management (CALM) is a treatment-delivery model for anxiety disorders encountered in primary care. CALM offers cognitive behavioral therapy ...

journal_title：Psychological medicine

authors： Joesch JM,Sherbourne CD,Sullivan G,Stein MB,Craske MG,Roy-Byrne P

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Interest in the mental health of women deployed to modern military campaigns is increasing, although research examining gender differences is limited. Little is known about experiences women have had on these deployments, or whether men and women respond differently to combat exposure. METHOD:The current st...

journal_title：Psychological medicine

authors： Woodhead C,Wessely S,Jones N,Fear NT,Hatch SL

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Despite methodological differences between studies, it has been suggested that psychopathy may be associated with a ventromedial prefrontal cortex (VMPFC) deficit and antisocial personality disorder (ASPD), as classified in the DSM-IV, with a broader range of deficits in dorsolateral prefrontal cortex (DLPFC...

journal_title：Psychological medicine

authors： Dolan M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The excess mortality following first-contact psychosis is well recognized. However, the causes of death in a complete incidence cohort and mortality patterns over time compared with the general population are unknown. METHOD:All 2723 patients who presented for the first time with psychosis in three defined ...

journal_title：Psychological medicine

authors： Dutta R,Murray RM,Allardyce J,Jones PB,Boydell JE

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Several conceptual models have been considered for the assessment of personality pathology in DSM-5. This study sought to extend our previous findings to compare the long-term predictive validity of three such models: the five-factor model (FFM), the schedule for nonadaptive and adaptive personality (SNAP), ...

journal_title：Psychological medicine

authors： Morey LC,Hopwood CJ,Markowitz JC,Gunderson JG,Grilo CM,McGlashan TH,Shea MT,Yen S,Sanislow CA,Ansell EB,Skodol AE

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The Wenchuan earthquake was a catastrophic earthquake in China. The aim of this study is to explore longitudinally the rates of post-traumatic stress disorder (PTSD) and depression in adolescents after the Wenchuan earthquake, and to identify independent predictors of PTSD. METHOD:PTSD and depression sympto...

journal_title：Psychological medicine

authors： Zhang Z,Ran MS,Li YH,Ou GJ,Gong RR,Li RH,Fan M,Jiang Z,Fang DZ

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Children whose parents die by, or attempt, suicide are believed to be at greater risk of suicidal behaviours and affective disorders. We systematically reviewed the literature on these associations and, using meta-analysis, estimated the strength of associations as well as investigated potential effect modif...

journal_title：Psychological medicine

authors： Geulayov G,Gunnell D,Holmen TL,Metcalfe C

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:According to the stress sensitization hypothesis, prior exposure to extreme stressors may lead to increased responsiveness to subsequent stressors. It is unclear whether disaster exposure is associated with stress sensitization and, if so, whether this effect is lasting or temporary. This study aimed to inve...

journal_title：Psychological medicine

authors： Smid GE,van der Velden PG,Lensvelt-Mulders GJ,Knipscheer JW,Gersons BP,Kleber RJ

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Depression is associated with alterations of emotional and cognitive processing, and executive control in particular. Previous research has shown that depressed patients are impaired in their ability to shift attention from one emotional category to another, but whether this shifting deficit is more evident ...

journal_title：Psychological medicine

authors： Murphy FC,Michael A,Sahakian BJ

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The increased occurrence of obstetric complications (OCs) in patients with schizophrenia suggests that alterations in neurodevelopment may be of importance to the aetiology of the illness. Abnormal cortical folding may reflect subtle deviation from normal neurodevelopment during the foetal or neonatal period...

journal_title：Psychological medicine

authors： Haukvik UK,Schaer M,Nesvåg R,McNeil T,Hartberg CB,Jönsson EG,Eliez S,Agartz I

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Converging evidence implicates basal ganglia alterations in impulsivity and suicidal behavior. For example, D2/D3 agonists and subthalamic nucleus stimulation in Parkinson's disease (PD) trigger impulse control disorders and possibly suicidal behavior. Furthermore, suicidal behavior has been associated with ...

journal_title：Psychological medicine

authors： Dombrovski AY,Siegle GJ,Szanto K,Clark L,Reynolds CF,Aizenstein H

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Major depressive disorder during pregnancy associates with potentially detrimental consequences for mother and child. The current study examined peripheral blood gene expression as a potential biomarker for prenatal depressive symptoms. METHOD:Maternal RNA from whole blood, plasma and the Beck Depression In...

journal_title：Psychological medicine

authors： Katz ER,Stowe ZN,Newport DJ,Kelley ME,Pace TW,Cubells JF,Binder EB

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:To date, magnetic resonance imaging (MRI) has made little impact on the diagnosis and monitoring of psychoses in individual patients. In this study, we used a support vector machine (SVM) whole-brain classification approach to predict future illness course at the individual level from MRI data obtained at th...

journal_title：Psychological medicine

authors： Mourao-Miranda J,Reinders AA,Rocha-Rego V,Lappin J,Rondina J,Morgan C,Morgan KD,Fearon P,Jones PB,Doody GA,Murray RM,Kapur S,Dazzan P

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Post-traumatic stress disorder (PTSD) develops in a minority of traumatized individuals. Attention biases to threat and abnormalities in fear learning and extinction are processes likely to play a critical role in the creation and/or maintenance of PTSD symptomatology. However, the relationship between these...

journal_title：Psychological medicine

authors： Fani N,Tone EB,Phifer J,Norrholm SD,Bradley B,Ressler KJ,Kamkwalala A,Jovanovic T

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:There are no tested methods for conducting epidemiological studies of autism spectrum disorders (ASDs) in adult general population samples. We tested the validity of the Autism Diagnostic Observation Schedule module-4 (ADOS-4) and the 20-item Autism-Spectrum Quotient (AQ-20). METHOD:Randomly sampled adults ...

journal_title：Psychological medicine

authors： Brugha TS,McManus S,Smith J,Scott FJ,Meltzer H,Purdon S,Berney T,Tantam D,Robinson J,Radley J,Bankart J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Studies have suggested that patients with schizophrenia are impaired at recognizing emotions. Recently, it has been shown that the neuropeptide oxytocin can have beneficial effects on social behaviors. METHOD:To examine emotion recognition deficits in patients and see whether oxytocin could improve these de...

journal_title：Psychological medicine

authors： Averbeck BB,Bobin T,Evans S,Shergill SS

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Alterations in self-monitoring have been reported in patients with psychotic disorders, but it remains unclear to what degree they represent true indicators of familial vulnerability for psychosis. METHOD:An error-correction action-monitoring task was used to examine self-monitoring in 42 patients with schi...

journal_title：Psychological medicine

authors： Hommes J,Krabbendam L,Versmissen D,Kircher T,van Os J,van Winkel R

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Electronic medical records (EMR) provide a unique opportunity for efficient, large-scale clinical investigation in psychiatry. However, such studies will require development of tools to define treatment outcome. METHOD:Natural language processing (NLP) was applied to classify notes from 127 504 patients wit...

journal_title：Psychological medicine

authors： Perlis RH,Iosifescu DV,Castro VM,Murphy SN,Gainer VS,Minnier J,Cai T,Goryachev S,Zeng Q,Gallagher PJ,Fava M,Weilburg JB,Churchill SE,Kohane IS,Smoller JW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Chronic fatigue is a common symptom of multiple sclerosis (MS). A randomized controlled trial (RCT) showed that cognitive behavioural therapy (CBT) was more effective in reducing MS fatigue than relaxation training (RT). The aim of the current study was to analyse additional data from this trial to determine...

journal_title：Psychological medicine

authors： Knoop H,van Kessel K,Moss-Morris R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Executive functions have been proposed as endophenotypes for attention deficit hyperactivity disorder (ADHD); however, data regarding visual memory are lacking. We therefore assessed visual memory in adolescents with ADHD and their unaffected siblings compared with controls. METHOD:The participants included...

journal_title：Psychological medicine

authors： Shang CY,Gau SS

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Cannabis use is considered a component cause of psychotic illness, interacting with genetic and other environmental risk factors. Little is known, however, about these putative interactions. The present study investigated whether an urban environment plays a role in moderating the effects of adolescent canna...

journal_title：Psychological medicine

authors： Kuepper R,van Os J,Lieb R,Wittchen HU,Henquet C

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Many studies have reported an increased incidence of psychiatric disorder (particularly psychotic disorders) among first generation adult immigrants, along with an increasing risk for ethnic minorities living in low-minority concentration neighborhoods. These studies have depended mostly on European case-bas...

journal_title：Psychological medicine

authors： Menezes NM,Georgiades K,Boyle MH

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Psychiatric disorders are common following traumatic brain injury (TBI). However, few studies have examined the course of disorder development and the influence of pre-injury psychiatric history. The present study aimed to examine the frequency of, and association between, psychiatric disorders occurring pre...

journal_title：Psychological medicine

authors： Gould KR,Ponsford JL,Johnston L,Schönberger M

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Both past depressive episodes and the personality trait of depressive rumination are strong risk factors for future depression. Depression is associated with abnormal emotional processing, which may be a neurobiological marker for vulnerability to depression. A consistent picture has yet to emerge as to how ...

journal_title：Psychological medicine

authors： Thomas EJ,Elliott R,McKie S,Arnone D,Downey D,Juhasz G,Deakin JF,Anderson IM

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:There are no risk models for the prediction of anxiety that may help in prevention. We aimed to develop a risk algorithm for the onset of generalized anxiety and panic syndromes. METHOD:Family practice attendees were recruited between April 2003 and February 2005 and followed over 24 months in the UK, Spain...

journal_title：Psychological medicine

authors： King M,Bottomley C,Bellón-Saameño JA,Torres-Gonzalez F,Švab I,Rifel J,Maaroos HI,Aluoja A,Geerlings MI,Xavier M,Carraça I,Vicente B,Saldivia S,Nazareth I

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Identifying prodromal features that predate the onset of bipolar disorder (BD) may enable the prevention of BD and aid early intervention. This review addresses two key questions: Is there a bipolar prodrome? And, if there is, what are its characteristic features? METHOD:A comprehensive search of databases ...

journal_title：Psychological medicine

authors： Howes OD,Lim S,Theologos G,Yung AR,Goodwin GM,McGuire P

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Depression increases the risk of subsequent vascular events in both cardiac and non-cardiac patients. Atherosclerosis, the underlying process leading to vascular events, has been associated with depression. This association, however, may be confounded by the somatic-affective symptoms being a consequence of ...

journal_title：Psychological medicine

authors： Bus BA,Marijnissen RM,Holewijn S,Franke B,Purandare N,de Graaf J,den Heijer M,Buitelaar JK,Voshaar RC

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Depressed individuals demonstrate a poorer ability to recognize the emotions of others, which could contribute to difficulties in interpersonal behaviour. This emotion recognition deficit appears related to the depressive state and is particularly pronounced when emotions are labelled semantically. Here, we ...

journal_title：Psychological medicine

authors： van Wingen GA,van Eijndhoven P,Tendolkar I,Buitelaar J,Verkes RJ,Fernández G

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:In people with bulimic eating disorders, exposure to high-calorie foods can result in increases in food craving, raised subjective stress and salivary cortisol concentrations. This cue-induced food craving can be reduced by repetitive transcranial magnetic stimulation (rTMS). We investigated whether rTMS has...

journal_title：Psychological medicine

authors： Claudino AM,Van den Eynde F,Stahl D,Dew T,Andiappan M,Kalthoff J,Schmidt U,Campbell IC

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Recent neurodevelopmental models of schizophrenia, together with substantial evidence of neurocognitive dysfunction among people with schizophrenia, have led to a widespread view that general cognitive deficits are a central aspect of schizophrenic pathology. However, the temporal relationships between intel...

journal_title：Psychological medicine

authors： Carter JW,Parnas J,Urfer-Parnas A,Watson J,Mednick SA

更新日期：2011-06-01 00:00:00